Speaker: Dr. Sun Fengzhu, professor of Quantitative and Computational Biology at the University of Southern California (USC)

Date: May 23, 2023

Time: 10:00-11:00

Location: Zhixin Building, Block B, 1248

Sponsor: School of Mathematics, Shandong University

Abstract:

Viruses play important roles in controlling bacterial population size, altering host metabolism, and have broader impacts on the functions of microbial communities, such as human gut, soil, and ocean microbiomes. However, the investigations of viruses and their functions were vastly underdeveloped. Metagenomic studies provide enormous resources for the identifications of novel viruses and their hosts. We developed several statistical and machine learning methods for the identification of virus-host interactions such as VirHostMatcher, VirHostMatcherNet, and ContigNet. We also developed computational methods for the analysis of metagnomic Hi-C data for metagenome assembly and for linking mobile genetic elements to their hosts. Applications of these tools to metagenomic data will help explore mobile genetic elements and their interactions with their hosts.

For more information, please visit:

https://www.view.sdu.edu.cn/info/1020/179932.htm